بررسی فراوانی و خصوصیات بالینی اسکلروز منتشر در بیماران مراجعه کننده به مرکز پزشکی شفا در کرمان طی سالهای 74- 1370

A clinicoepidemiologic study has been done on patients with muliple sclerosis from 1991-1994 in Shafa Hospital in Kerman. Diagnostic criteria were based on clinical findings and brain and spine MRI scanning. The patients were followed for 1-5 years. 60 patients were diagnosed of whom 30 were from Kerman city. Female to male ratio is 1.14/1. The patients had no family history for multiple sclerosis. The onset of disease was mostly in the third decade of life. The most common clinical signs and symptoms were in this order: dizziness (81.7%), fatigability (75%), lower extremities spastic paresia (68.7%), sphincteric disorders (55%), ataxia (48.3%), visual loss (45%), Lhermitte sign (40%), diplopia (36.6%), moderate or sever psychiatric disorders(31. 7%), dysarticulation (11.7%) and seizure (5%)